ARHGAP24 anticorps (AA 501-600)
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- Antigène Voir toutes ARHGAP24 Anticorps
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
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Épitope
- AA 501-600
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARHGAP24 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Homologie
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ARHGAP24
- Isotype
- IgG
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
- Autre désignation
- ARHGAP24 (ARHGAP24 Produits)
- Synonymes
- anticorps FILGAP, anticorps RC-GAP72, anticorps RCGAP72, anticorps p73, anticorps p73RhoGAP, anticorps 0610025G21Rik, anticorps si:ch211-65i12.2, anticorps Rho GTPase activating protein 24, anticorps ARHGAP24, anticorps Arhgap24, anticorps arhgap24
- Sujet
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Synonyms: Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, ARHGAP24, FILGAP
Background: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
- ID gène
- 83478
- UniProt
- Q8N264
- Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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