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ARHGAP24 anticorps (AA 501-600)

ARHGAP24 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN714716
  • Antigène Voir toutes ARHGAP24 Anticorps
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Épitope
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    AA 501-600
    Reactivité
    • 27
    • 10
    • 10
    • 1
    • 1
    Humain
    Hôte
    • 25
    • 2
    Lapin
    Clonalité
    • 27
    Polyclonal
    Conjugué
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ARHGAP24 est non-conjugé
    Application
    • 20
    • 16
    • 3
    Western Blotting (WB), ELISA
    Homologie
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ARHGAP24
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Autre désignation
    ARHGAP24 (ARHGAP24 Produits)
    Synonymes
    anticorps FILGAP, anticorps RC-GAP72, anticorps RCGAP72, anticorps p73, anticorps p73RhoGAP, anticorps 0610025G21Rik, anticorps si:ch211-65i12.2, anticorps Rho GTPase activating protein 24, anticorps ARHGAP24, anticorps Arhgap24, anticorps arhgap24
    Sujet

    Synonyms: Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, ARHGAP24, FILGAP

    Background: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

    ID gène
    83478
    UniProt
    Q8N264
    Pathways
    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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