APOB anticorps

N° du produit ABIN7189848

Détail du produit anti-APOB anticorps

Antigène: APOB (Apolipoprotein B (APOB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOB est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human APOB

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:5000, IHC:1:15-1:50,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur APOB

Antigène: APOB (Apolipoprotein B (APOB))

Autre désignation: APOB (APOB Produits)

Synonymes: anticorps FLDB, anticorps LDLCQ4, anticorps Ac1-060, anticorps Apo B-100, anticorps ApoB-100, anticorps ApoB-48, anticorps AI315052, anticorps apob-100, anticorps apob-48, anticorps APOB-100, anticorps ApoB(100), anticorps APOB, anticorps apolipoprotein B, anticorps APOB, anticorps Apob

Sujet:

Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Aliases: Apo B 100 antibody, Apo B antibody, Apo B-100 antibody, Apo B-48 antibody, Apo B100 antibody, Apo B48 antibody, ApoB 100 antibody, ApoB 48 antibody, APOB antibody, APOB_HUMAN antibody, Apolipoprotein B (including Ag(x) antigen) antibody, Apolipoprotein B 100 antibody, Apolipoprotein B 48 antibody, Apolipoprotein B antibody, Apolipoprotein B-48 antibody, Apolipoprotein B100 antibody, Apolipoprotein B48 antibody, FLDB antibody, LDLCQ4 antibody

UniProt: P04114

Pathways: Lipid Metabolism