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SPAG1 anticorps

SPAG1 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7192612
  • Antigène Voir toutes SPAG1 Anticorps
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    Reactivité
    • 29
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 28
    • 1
    Lapin
    Clonalité
    • 29
    Polyclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPAG1 est non-conjugé
    Application
    • 22
    • 15
    • 15
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Antigen affinity purification
    Immunogène
    Synthetic peptide of Human SPAG1
    Isotype
    IgG
    Top Product
    Discover our top product SPAG1 Anticorps primaire
  • Indications d'application
    ELISA:1:1000-1:5000, IHC:1:25-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    Autre désignation
    SPAG1 (SPAG1 Produits)
    Synonymes
    anticorps cb1089, anticorps MGC162178, anticorps wu:fj78g10, anticorps sp75, anticorps tpis, anticorps hsd-3.8, anticorps HSD-3.8, anticorps SP75, anticorps TPIS, anticorps sperm associated antigen 1, anticorps sperm associated antigen 1a, anticorps SPAG1, anticorps spag1a, anticorps CpipJ_CPIJ006297, anticorps spag1, anticorps Spag1
    Sujet

    Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.

    Aliases: SPAG1 antibody, Sperm-associated antigen 1 antibody, HSD-3.8 antibody, Infertility-related sperm protein Spag-1 antibody

    UniProt
    Q07617
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