CD46 anticorps (AA 35-179)

N° du produit ABIN7193208

Détail du produit anti-CD46 anticorps

Antigène: CD46

Épitope: AA 35-179

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)

Fonction: CD46 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD46 (AA: 35-179) expressed in E. Coli.

Clone: 1A5A5

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CD46

Antigène: CD46

Autre désignation: CD46 (CD46 Produits)

Sujet:

Description:

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Aliases: MCP, TLX, AHUS2, MIC10, TRA2.10

Poids moléculaire: 43.7kDa

ID gène: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization