IL21 Receptor anticorps (AA 20-232)
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- Antigène Voir toutes IL21 Receptor (IL21R) Anticorps
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
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Épitope
- AA 20-232
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IL21 Receptor est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS)
- Fonction
- CD360 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CD360 (AA: 20-232) expressed in E. Coli.
- Clone
- 8H10G4D12
- Isotype
- IgG1
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- Autre désignation
- CD360 (IL21R Produits)
- Sujet
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Description:
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
Aliases: IL21R, NILR, IMD56
- Poids moléculaire
- 59.1kDa
- ID gène
- 50615
- UniProt
- Q9HBE5
- Pathways
- Signalistation JAK/STAT
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