TEK anticorps (AA 571-748)

N° du produit ABIN7193241

Détail du produit anti-TEK anticorps

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Épitope: AA 571-748

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TEK est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: CD202B Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD202B (AA: 571-748) expressed in E. Coli.

Clone: 3F5B9

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur TEK

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Autre désignation: CD202B (TEK Produits)

Synonymes: anticorps TEK, anticorps DKFZp469E064, anticorps AA517024, anticorps Cd202b, anticorps Hyk, anticorps Tie2, anticorps tie-2, anticorps CD202B, anticorps TIE-2, anticorps TIE2, anticorps VMCM, anticorps VMCM1, anticorps Tie-2, anticorps tie2, anticorps TEK receptor tyrosine kinase, anticorps angiopoietin-1 receptor, anticorps TEK tyrosine kinase, endothelial, anticorps TEK, anticorps LOC100408334, anticorps tek, anticorps Tek

Sujet:

Description:

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Aliases: TEK, TIE2, VMCM, GLC3E, TIE-2, VMCM1

Poids moléculaire: 125.8kDa,

ID gène: 7010

UniProt: Q02763

Pathways: Signalisation RTK, Growth Factor Binding