LRP6 anticorps (AA 1198-1370)
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- Antigène Voir toutes LRP6 Anticorps
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
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Épitope
- AA 1198-1370
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LRP6 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human LRP6 (AA: extra 1198-1370) expressed in E. coli.
- Clone
- 1A3F5
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
- Autre désignation
- LRP6 (LRP6 Produits)
- Synonymes
- anticorps lrp6-A, anticorps Xlrp6, anticorps adcad2, anticorps lrp6, anticorps LRP6, anticorps ADCAD2, anticorps C030016K15Rik, anticorps Cd, anticorps Gw, anticorps LDL receptor related protein 6, anticorps LDL receptor related protein 6 L homeolog, anticorps LDL receptor related protein 6 S homeolog, anticorps low density lipoprotein receptor-related protein 6, anticorps low-density lipoprotein receptor-related protein 6, anticorps LRP6, anticorps lrp6.L, anticorps lrp6.S, anticorps lrp6, anticorps Lrp6, anticorps LOC590395
- Sujet
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Description: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Aliases: ADCAD2, STHAG7
- Poids moléculaire
- 180 kDa
- ID gène
- 4040
- Pathways
- Signalisation WNT, Tube Formation
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