IL5RA anticorps (AA 21-196)

N° du produit ABIN7193317

Détail du produit anti-IL5RA anticorps

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Épitope: AA 21-196

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL5RA est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: CD125 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD125 (AA: 21-196) expressed in E. Coli.

Clone: 5E12F5D6

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur IL5RA

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Autre désignation: CD125 (IL5RA Produits)

Synonymes: anticorps MGC86517, anticorps IL5RA, anticorps il5r, anticorps cdw125, anticorps hsil5r3, anticorps gpIL-5ra, anticorps CD125, anticorps CDw125, anticorps HSIL5R3, anticorps IL5R, anticorps Il5r, anticorps interleukin 5 receptor subunit alpha L homeolog, anticorps interleukin 5 receptor subunit alpha, anticorps interleukin 5 receptor, alpha, anticorps il5ra.L, anticorps IL5RA, anticorps il5ra, anticorps Il5ra

Sujet:

Description:

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Aliases: IL5RA, IL5R, CDw125, HSIL5R3

Poids moléculaire: 47.7kDa

ID gène: 3568

Pathways: Signalistation JAK/STAT