CD27 anticorps (AA 20-144)
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- Antigène Voir toutes CD27 Anticorps
- CD27 (CD27 Molecule (CD27))
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Épitope
- AA 20-144
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD27 est non-conjugé
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Application
- Flow Cytometry (FACS), ELISA
- Fonction
- CD27 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CD27 (AA: 20-144) expressed in E. Coli.
- Clone
- 3B6D3
- Isotype
- IgG1
- Top Product
- Discover our top product CD27 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- CD27 (CD27 Molecule (CD27))
- Autre désignation
- CD27 (CD27 Produits)
- Synonymes
- anticorps TNFRSF7, anticorps S152, anticorps Tnfrsf7, anticorps Tp55, anticorps S152. LPFS2, anticorps T14, anticorps CD27 molecule, anticorps CD27 antigen, anticorps CD27, anticorps Cd27
- Sujet
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Description:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Aliases: T14, S152, Tp55, TNFRSF7, S152. LPFS2
- Poids moléculaire
- 29.1kDa
- ID gène
- 939
- UniProt
- P26842
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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