TLR9 anticorps (AA 26-193)
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- Antigène Voir toutes TLR9 Anticorps
- TLR9 (Toll-Like Receptor 9 (TLR9))
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Épitope
- AA 26-193
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TLR9 est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS)
- Fonction
- CD289 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CD289 (AA: 26-193) expressed in E. Coli.
- Clone
- 5B10E8
- Isotype
- IgG1
- Top Product
- Discover our top product TLR9 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- TLR9 (Toll-Like Receptor 9 (TLR9))
- Autre désignation
- CD289 (TLR9 Produits)
- Synonymes
- anticorps CD289, anticorps toll like receptor 9, anticorps toll-like receptor 9, anticorps TLR9, anticorps Tlr9
- Sujet
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Description:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Aliases: TLR9
- Poids moléculaire
- 116kDa
- ID gène
- 54106
- UniProt
- Q9NR96
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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