MTA1 anticorps (AA 541-715)
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- Antigène Voir toutes MTA1 Anticorps
- MTA1 (Metastasis Associated 1 (MTA1))
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Épitope
- AA 541-715
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MTA1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Fonction
- MTA1 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human MTA1 (AA: 541-715) expressed in E. Coli.
- Clone
- 6B1E9
- Isotype
- IgG2b
- Top Product
- Discover our top product MTA1 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- MTA1 (Metastasis Associated 1 (MTA1))
- Autre désignation
- MTA1 (MTA1 Produits)
- Synonymes
- anticorps Tex22, anticorps metastasis associated 1, anticorps metastasis associated 1 L homeolog, anticorps MTA1, anticorps Mta1, anticorps mta1.L
- Sujet
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This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
- Poids moléculaire
- 80.8kDa
- ID gène
- 9112
- UniProt
- Q13330
- Pathways
- Chromatin Binding
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