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MTA1 anticorps (AA 541-715)

MTA1 Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 6B1E9 unconjugated
N° du produit ABIN7193370
  • Antigène Voir toutes MTA1 Anticorps
    MTA1 (Metastasis Associated 1 (MTA1))
    Épitope
    • 14
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 541-715
    Reactivité
    • 53
    • 26
    • 22
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 6
    • 1
    Souris
    Clonalité
    • 48
    • 6
    Monoclonal
    Conjugué
    • 37
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MTA1 est non-conjugé
    Application
    • 42
    • 25
    • 11
    • 11
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Fonction
    MTA1 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human MTA1 (AA: 541-715) expressed in E. Coli.
    Clone
    6B1E9
    Isotype
    IgG2b
    Top Product
    Discover our top product MTA1 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    MTA1 (Metastasis Associated 1 (MTA1))
    Autre désignation
    MTA1 (MTA1 Produits)
    Synonymes
    anticorps Tex22, anticorps metastasis associated 1, anticorps metastasis associated 1 L homeolog, anticorps MTA1, anticorps Mta1, anticorps mta1.L
    Sujet

    This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

    Poids moléculaire
    80.8kDa
    ID gène
    9112
    UniProt
    Q13330
    Pathways
    Chromatin Binding
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