PIDD anticorps (AA 776-910)
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- Antigène Voir toutes PIDD Anticorps
- PIDD (P53-Induced Death Domain Protein (PIDD))
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Épitope
- AA 776-910
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PIDD est non-conjugé
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. coli.
- Clone
- 3C5G8
- Isotype
- IgG1
- Top Product
- Discover our top product PIDD Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: N/A, ICC: N/A, IHC: N/A
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- PIDD (P53-Induced Death Domain Protein (PIDD))
- Autre désignation
- PIDD1 (PIDD Produits)
- Synonymes
- anticorps 1200011D09Rik, anticorps AU042446, anticorps Pidd, anticorps LRDD, anticorps Lrdd, anticorps p53 induced death domain protein 1, anticorps p53-induced death domain protein 1, anticorps Pidd1, anticorps PIDD1
- Sujet
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Description: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Aliases: LRDD, PIDD
- Poids moléculaire
- 99.7 kDa
- ID gène
- 55367
- Pathways
- Signalisation p53, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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