PIDD anticorps (AA 776-910)

N° du produit ABIN7193396

Détail du produit anti-PIDD anticorps

Antigène: PIDD (P53-Induced Death Domain Protein (PIDD))

Épitope: AA 776-910

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PIDD est non-conjugé

Application: ELISA

Fonction: PIDD1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.

Clone: 3C5G8

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PIDD

Antigène: PIDD (P53-Induced Death Domain Protein (PIDD))

Autre désignation: PIDD1 (PIDD Produits)

Synonymes: anticorps 1200011D09Rik, anticorps AU042446, anticorps Pidd, anticorps LRDD, anticorps Lrdd, anticorps p53 induced death domain protein 1, anticorps p53-induced death domain protein 1, anticorps Pidd1, anticorps PIDD1

Sujet:

Description:

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Aliases: LRDD, PIDD

Poids moléculaire: 99.7kDa

ID gène: 55367

UniProt: Q9HB75

Pathways: Signalisation p53, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity