IL15RA anticorps (AA 31-205)
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- Antigène Voir toutes IL15RA Anticorps
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
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Épitope
- AA 31-205
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IL15RA est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Fonction
- CD215 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CD215 (AA: 31-205) expressed in E. Coli.
- Clone
- 5F10D9
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- Autre désignation
- CD215 (IL15RA Produits)
- Sujet
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Description:
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]
Aliases: IL15RA
- Poids moléculaire
- 28.2kDa
- ID gène
- 3601
- Pathways
- Signalistation JAK/STAT
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