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FADD anticorps (AA 20-150)

FADD Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 5A6A2 unconjugated
N° du produit ABIN7193411
  • Antigène Voir toutes FADD Anticorps
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Épitope
    • 17
    • 15
    • 14
    • 8
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-150
    Reactivité
    • 83
    • 49
    • 19
    • 17
    • 15
    Humain
    Hôte
    • 86
    • 14
    Souris
    Clonalité
    • 82
    • 18
    Monoclonal
    Conjugué
    • 61
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FADD est non-conjugé
    Application
    • 82
    • 43
    • 30
    • 15
    • 15
    • 12
    • 9
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    ELISA, Flow Cytometry (FACS)
    Fonction
    FADD Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human FADD (AA: 20-150) expressed in E. Coli.
    Clone
    5A6A2
    Isotype
    IgG1
    Top Product
    Discover our top product FADD Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Autre désignation
    FADD (FADD Produits)
    Sujet

    Description:

    The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]

    Aliases: GIG3, MORT1

    Poids moléculaire
    23.3kDa
    ID gène
    8772
    UniProt
    Q13158
    Pathways
    Apoptose, Signalisation TLR, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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