SETD2 anticorps (AA 2054-2245)

N° du produit ABIN7193416

Détail du produit anti-SETD2 anticorps

Antigène: SETD2 (SET Domain Containing 2 (SETD2))

Épitope: AA 2054-2245

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SETD2 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: SETD2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SETD2 (AA: 2054-2245) expressed in E. Coli.

Clone: 4G11E6

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur SETD2

Antigène: SETD2 (SET Domain Containing 2 (SETD2))

Autre désignation: SETD2 (SETD2 Produits)

Synonymes: anticorps Kif9, anticorps HBP231, anticorps HIF-1, anticorps HIP-1, anticorps HYPB, anticorps KMT3A, anticorps SET2, anticorps p231HBP, anticorps SET domain containing 2, anticorps Setd2, anticorps SETD2

Sujet:

Description:

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]

Aliases: LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

Poids moléculaire: 287.6kDa

ID gène: 29072

Pathways: Tube Formation