ATR anticorps (AA 366-550)
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- Antigène Voir toutes ATR Anticorps
- ATR (ATR serine/threonine kinase (ATR))
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Épitope
- AA 366-550
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ATR est non-conjugé
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Application
- ELISA, Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. coli.
- Clone
- 3G6D2
- Isotype
- IgG1
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- Indications d'application
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- ATR (ATR serine/threonine kinase (ATR))
- Autre désignation
- ATR (ATR Produits)
- Synonymes
- anticorps FCTCS, anticorps FRP1, anticorps MEC1, anticorps SCKL, anticorps SCKL1, anticorps ATR serine/threonine kinase, anticorps ataxia telangiectasia and Rad3 related, anticorps ATR, anticorps Atr
- Sujet
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Description: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Aliases: FRP1, MEC1, SCKL, FCTCS, SCKL1
- Poids moléculaire
- 301 kDa
- ID gène
- 545
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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