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ATR anticorps (AA 366-550)

ATR Reactivité: Humain ELISA, WB, FACS Hôte: Souris Monoclonal 3G6D2 unconjugated
N° du produit ABIN7193431
  • Antigène Voir toutes ATR Anticorps
    ATR (ATR serine/threonine kinase (ATR))
    Épitope
    • 11
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 366-550
    Reactivité
    • 45
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 4
    • 2
    Souris
    Clonalité
    • 43
    • 3
    Monoclonal
    Conjugué
    • 30
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATR est non-conjugé
    Application
    • 26
    • 21
    • 20
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. coli.
    Clone
    3G6D2
    Isotype
    IgG1
  • Indications d'application
    WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    ATR (ATR serine/threonine kinase (ATR))
    Autre désignation
    ATR (ATR Produits)
    Synonymes
    anticorps FCTCS, anticorps FRP1, anticorps MEC1, anticorps SCKL, anticorps SCKL1, anticorps ATR serine/threonine kinase, anticorps ataxia telangiectasia and Rad3 related, anticorps ATR, anticorps Atr
    Sujet

    Description: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

    Aliases: FRP1, MEC1, SCKL, FCTCS, SCKL1

    Poids moléculaire
    301 kDa
    ID gène
    545
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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