ATR anticorps (AA 366-550)

N° du produit ABIN7193431

Détail du produit anti-ATR anticorps

Antigène: ATR (ATR serine/threonine kinase (ATR))

Épitope: AA 366-550

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATR est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: ATR Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. Coli.

Clone: 3G6D2

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur ATR

Antigène: ATR (ATR serine/threonine kinase (ATR))

Autre désignation: ATR (ATR Produits)

Synonymes: anticorps FCTCS, anticorps FRP1, anticorps MEC1, anticorps SCKL, anticorps SCKL1, anticorps ATR serine/threonine kinase, anticorps ataxia telangiectasia and Rad3 related, anticorps ATR, anticorps Atr

Sujet:

Description:

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

Aliases: FRP1, MEC1, SCKL, FCTCS, SCKL1

Poids moléculaire: 301kDa

ID gène: 545

UniProt: Q13535

Pathways: Positive Regulation of Response to DNA Damage Stimulus