Rubicon anticorps (AA 859-972)
-
- Antigène Voir toutes Rubicon (KIAA0226) Anticorps
- Rubicon (KIAA0226) (KIAA0226)
-
Épitope
- AA 859-972
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp Rubicon est non-conjugé
-
Application
- ELISA
- Fonction
- RUBCN Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. Coli.
- Clone
- 4F5B5
- Isotype
- IgG1
- Top Product
- Discover our top product KIAA0226 Anticorps primaire
-
-
- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- Antigène
- Rubicon (KIAA0226) (KIAA0226)
- Autre désignation
- RUBCN (KIAA0226 Produits)
- Synonymes
- anticorps RUBICON, anticorps 5330403K09, anticorps Kiaa0226, anticorps Rubicon, anticorps mKIAA0226, anticorps RUN and cysteine rich domain containing beclin 1 interacting protein, anticorps KIAA0226, anticorps RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein, anticorps RUBCN, anticorps KIAA0226, anticorps Rubcn
- Sujet
-
Description:
The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Aliases: SCAR15, RUBICON, KIAA0226
- Poids moléculaire
- 108.6kDa
- ID gène
- 9711
- UniProt
- Q92622
- Pathways
- Autophagy
-