Caspase 9 anticorps (AA 331-416)
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- Antigène Voir toutes Caspase 9 (CASP9) Anticorps
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Épitope
- AA 331-416
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Caspase 9 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human CASP9 (AA: 331-416) expressed in E. coli.
- Clone
- 5E8C8
- Isotype
- IgG1
- Top Product
- Discover our top product CASP9 Anticorps primaire
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- Indications d'application
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- Autre désignation
- CASP9 (CASP9 Produits)
- Synonymes
- anticorps CASP9, anticorps AI115399, anticorps APAF-3, anticorps AW493809, anticorps CASP-9, anticorps Caspase-9, anticorps ICE-LAP6, anticorps Mch6, anticorps Apaf3, anticorps Casp-9-CTD, anticorps Casp9_v1, anticorps Ice-Lap6, anticorps APAF3, anticorps MCH6, anticorps PPP1R56, anticorps caspase 9, anticorps CASP9, anticorps Casp9
- Sujet
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Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1, this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Aliases: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6
- Poids moléculaire
- 46.3 kDa
- ID gène
- 842
- Pathways
- Signalisation MAPK, Signalisation RTK, Apoptose, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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