NOXA anticorps (AA 1-54)

N° du produit ABIN7193484

Cet anticorps anti-NOXA Monoclonal Souris (Clone 1A2D3) (ABIN7193484) détecte spécifiquement NOXA dans ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NOXA anticorps (AA 1-54) (ABIN7193484)

Antigène: NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOXA est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 1A2D3

Détail du produit anti-NOXA anticorps

Épitope: AA 1-54

Fonction: PMAIP1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PMAIP1 (AA: 1-54) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur NOXA

Antigène: NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Autre désignation: PMAIP1

Sujet:

The protein encoded by this gene promotes activation of caspases and apoptosis, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Poids moléculaire: 6 kDa

ID gène: 5366

UniProt: Q13794

Pathways: Signalisation p53, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus