NOXA anticorps (AA 1-54)
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- Antigène Voir toutes NOXA (PMAIP1) Anticorps
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
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Épitope
- AA 1-54
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NOXA est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS)
- Fonction
- PMAIP1 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human PMAIP1 (AA: 1-54) expressed in E. Coli.
- Clone
- 1A2D3
- Isotype
- IgG1
- Top Product
- Discover our top product PMAIP1 Anticorps primaire
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anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-54) antibody
PMAIP1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibodyPMAIP1 Reactivité: Humain WB, IHC Hôte: Souris Monoclonal 114C307-1 unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (Internal Region) antibodyVerified PMAIP1 Reactivité: Humain WB, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (N-Term) antibodyPMAIP1 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
- Autre désignation
- PMAIP1 (PMAIP1 Produits)
- Synonymes
- anticorps TN3, anticorps PMAIP1, anticorps zgc:162379, anticorps APR, anticorps NOXA, anticorps Noxa, anticorps phorbol-12-myristate-13-acetate-induced protein 1, anticorps PMAIP1, anticorps pmaip1, anticorps Pmaip1
- Sujet
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Description:
The protein encoded by this gene promotes activation of caspases and apoptosis, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Aliases: APR, NOXA
- Poids moléculaire
- 6kDa
- ID gène
- 5366
- UniProt
- Q13794
- Pathways
- Signalisation p53, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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