CD8 alpha anticorps (AA 22-235)
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- Antigène Voir toutes CD8 alpha (CD8A) Anticorps
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Épitope
- AA 22-235
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD8 alpha est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA
- Fonction
- CD8a Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CD8a (AA: 22-235) expressed in E. Coli.
- Clone
- 8H8A8
- Isotype
- IgG1
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Autre désignation
- CD8a (CD8A Produits)
- Synonymes
- anticorps cd8, anticorps LOC100136450, anticorps BB154331, anticorps Ly-2, anticorps Ly-35, anticorps Ly-B, anticorps Lyt-2, anticorps zgc:136643, anticorps CD8, anticorps Leu2, anticorps MAL, anticorps p32, anticorps RHACD8-4, anticorps CD8a molecule, anticorps uncharacterized LOC100125537, anticorps CD8 alpha, anticorps CD8 antigen, alpha chain, anticorps T-cell surface glycoprotein CD8 alpha chain, anticorps Cd8a, anticorps LOC100125537, anticorps LOC100136450, anticorps CD8A, anticorps cd8a, anticorps LOC100126556
- Sujet
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Description:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: CD8, p32, Leu2
- Poids moléculaire
- 25.7kDa
- ID gène
- 925
- UniProt
- P01732
- Pathways
- TCR Signaling
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