MSH2 anticorps (AA 442-586)
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- Antigène Voir toutes MSH2 Anticorps
- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Épitope
- AA 442-586
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MSH2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Fonction
- MSH2 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human MSH2 (AA: 442-586) expressed in E. Coli.
- Clone
- 2E2C7
- Isotype
- IgG1
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Autre désignation
- MSH2 (MSH2 Produits)
- Synonymes
- anticorps COCA1, anticorps FCC1, anticorps HNPCC, anticorps HNPCC1, anticorps LCFS2, anticorps AI788990, anticorps wu:fc06b02, anticorps wu:fc13e09, anticorps zgc:55333, anticorps ATMSH2, anticorps MUTS homolog 2, anticorps msh2, anticorps mutS homolog 2, anticorps mutS homolog 2 (E. coli), anticorps MUTS homolog 2, anticorps mutS homolog 2 L homeolog, anticorps MutS protein homolog 2, anticorps MSH2, anticorps Msh2, anticorps msh2, anticorps msh2.L
- Sujet
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Description:
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Aliases: FCC1, COCA1, HNPCC, LCFS2, hMSH2, HNPCC1
- Poids moléculaire
- 104.7kDa
- ID gène
- 4436
- UniProt
- P43246
- Pathways
- Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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