MSH6 anticorps (AA 217-395)
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- Antigène Voir toutes MSH6 Anticorps
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Épitope
- AA 217-395
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MSH6 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Fonction
- MSH6 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human MSH6 (AA: 217-395) expressed in E. Coli.
- Clone
- 1D1C2
- Isotype
- IgG1
- Top Product
- Discover our top product MSH6 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
- Autre désignation
- MSH6 (MSH6 Produits)
- Synonymes
- anticorps GTBP, anticorps GTMBP, anticorps HNPCC5, anticorps HSAP, anticorps p160, anticorps cb326, anticorps wu:fb36c12, anticorps LOC100227810, anticorps AU044881, anticorps AW550279, anticorps Gtmbp, anticorps mutS homolog 6, anticorps mutS homolog 6 (E. coli), anticorps DNA mismatch repair protein, anticorps MSH6, anticorps msh6, anticorps Msh6
- Sujet
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Description:
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Aliases: GTBP, HSAP, p160, GTMBP, HNPCC5
- Poids moléculaire
- 152.8kDa
- ID gène
- 2956
- UniProt
- P52701
- Pathways
- Réparation de l'ADN, Chromatin Binding, Production of Molecular Mediator of Immune Response
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