LIFR anticorps (AA 22-441)
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- Antigène Voir toutes LIFR Anticorps
- LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
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Épitope
- AA 22-441
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LIFR est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS)
- Fonction
- CD118 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human PLA2G7 (AA: 22-441) expressed in E. Coli.
- Clone
- 5D3G12
- Isotype
- IgG1
- Top Product
- Discover our top product LIFR Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
- Autre désignation
- CD118 (LIFR Produits)
- Synonymes
- anticorps A230075M04Rik, anticorps AW061234, anticorps LIF, anticorps CD118, anticorps LIF-R, anticorps SJS2, anticorps STWS, anticorps SWS, anticorps leukemia inhibitory factor receptor, anticorps LIF receptor alpha, anticorps leukemia inhibitory factor receptor alpha, anticorps Lifr, anticorps LOC397451, anticorps LIFR
- Sujet
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Description:
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene.
Aliases: LIFR, SWS, SJS2, STWS, LIF-R
- Poids moléculaire
- 123.7kDa
- ID gène
- 3977
- UniProt
- P42702
- Pathways
- Signalistation JAK/STAT, Growth Factor Binding
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