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LIFR anticorps (AA 22-441)

LIFR Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 5D3G12 unconjugated
N° du produit ABIN7193531
  • Antigène Voir toutes LIFR Anticorps
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    Épitope
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-441
    Reactivité
    • 38
    • 14
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 53
    • 6
    Souris
    Clonalité
    • 54
    • 5
    Monoclonal
    Conjugué
    • 28
    • 15
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LIFR est non-conjugé
    Application
    • 46
    • 20
    • 19
    • 9
    • 9
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Fonction
    CD118 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human PLA2G7 (AA: 22-441) expressed in E. Coli.
    Clone
    5D3G12
    Isotype
    IgG1
    Top Product
    Discover our top product LIFR Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    Autre désignation
    CD118 (LIFR Produits)
    Sujet

    Description:

    This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene.

    Aliases: LIFR, SWS, SJS2, STWS, LIF-R

    Poids moléculaire
    123.7kDa
    ID gène
    3977
    UniProt
    P42702
    Pathways
    Signalistation JAK/STAT, Growth Factor Binding
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