Asialoglycoprotein Receptor 2 anticorps (AA 80-311)

N° du produit ABIN7193549

Détail du produit anti-Asialoglycoprotein Receptor 2 anticorps

Antigène: Asialoglycoprotein Receptor 2 (ASGR2)

Épitope: AA 80-311

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Asialoglycoprotein Receptor 2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Fonction: ASGR2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ASGR2 (AA: 80-311) expressed in E. Coli.

Clone: 2C6D11

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Asialoglycoprotein Receptor 2

Antigène: Asialoglycoprotein Receptor 2 (ASGR2)

Autre désignation: ASGR2 (ASGR2 Produits)

Synonymes: anticorps ASGR2, anticorps asgr2, anticorps MGC137129, anticorps ASGP-R2, anticorps ASGPR2, anticorps CLEC4H2, anticorps HBXBP, anticorps HL-2, anticorps Asgr, anticorps Asgr-2, anticorps asialoglycoprotein receptor 2, anticorps C-type lectin domain family 10 member A, anticorps ASGR2, anticorps clec10a, anticorps Asgr2, anticorps LOC100347178

Sujet:

Description:

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Aliases: HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2

Poids moléculaire: 35kDa

ID gène: 433

UniProt: P07307

Pathways: Thyroid Hormone Synthesis