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HAS1 anticorps

HAS1 Reactivité: Humain ELISA, FACS, ICC Hôte: Souris Monoclonal 5B5B4 unconjugated
N° du produit ABIN7193594
  • Antigène Voir toutes HAS1 Anticorps
    HAS1 (Hyaluronan Synthase 1 (HAS1))
    Reactivité
    • 55
    • 29
    • 22
    • 5
    • 5
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 50
    • 6
    Souris
    Clonalité
    • 50
    • 6
    Monoclonal
    Conjugué
    • 18
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HAS1 est non-conjugé
    Application
    • 26
    • 24
    • 18
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Fonction
    HAS1 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human HAS1 (AA: (74-399)) expressed in E. Coli.
    Clone
    5B5B4
    Isotype
    IgG2b
    Top Product
    Discover our top product HAS1 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200-1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    HAS1 (Hyaluronan Synthase 1 (HAS1))
    Autre désignation
    HAS1 (HAS1 Produits)
    Synonymes
    anticorps dg42, anticorps Xhas1, anticorps HAS, anticorps shas1, anticorps hyaluronan synthase 1, anticorps hyaluronan synthase 1 S homeolog, anticorps has1, anticorps HAS1, anticorps Has1, anticorps has1.S
    Sujet

    Description:

    Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

    Aliases: HAS

    Poids moléculaire
    65kDa
    ID gène
    3036
    UniProt
    Q92839
    Pathways
    Glycosaminoglycan Metabolic Process
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