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MYLK anticorps (AA 1375-1524)

MYLK Reactivité: Humain WB, ELISA, IHC, ICC, FACS Hôte: Souris Monoclonal 7F2B11 unconjugated
N° du produit ABIN7193606
  • Antigène Voir toutes MYLK Anticorps
    MYLK (Myosin Light Chain Kinase (MYLK))
    Épitope
    • 15
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1375-1524
    Reactivité
    • 62
    • 40
    • 35
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 71
    • 3
    • 3
    • 1
    Souris
    Clonalité
    • 65
    • 13
    Monoclonal
    Conjugué
    • 39
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MYLK est non-conjugé
    Application
    • 38
    • 33
    • 22
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Fonction
    MYLK Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human MYLK (AA:1375-1524) expressed in E. Coli.
    Clone
    7F2B11
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200-1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    MYLK (Myosin Light Chain Kinase (MYLK))
    Autre désignation
    MYLK (MYLK Produits)
    Sujet

    Description:

    This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

    Aliases: KRP, AAT7, MLCK, MLCK1, MMIHS, MYLK1, s mMLCK, MLCK108, MLCK210, MSTP083

    Poids moléculaire
    210kDa
    ID gène
    4638
    UniProt
    Q15746
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