MUC16 anticorps (AA 1-200)

N° du produit ABIN7193615

Détail du produit anti-MUC16 anticorps

Antigène: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Épitope: AA 1-200

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC16 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human MUC16 (AA: extra 1-200) expressed in E. coli.

Clone: 4C8C8

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur MUC16

Antigène: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Autre désignation: MUC16 (CA125 Produits)

Synonymes: anticorps CA125, anticorps 1110008I14Rik, anticorps Ca125, anticorps Gm1480, anticorps RGD1308422, anticorps MUC16, anticorps mucin 16, cell surface associated, anticorps mucin 16, anticorps mucin-16, anticorps MUC16, anticorps Muc16, anticorps LOC476718, anticorps LOC712735

Sujet:

Description: This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.

Aliases: CA125

Poids moléculaire: 1519 kDa

ID gène: 94025