CDKN1C anticorps
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- Antigène Voir toutes CDKN1C Anticorps
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CDKN1C est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Fonction
- CDKN1C Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CDKN1C expressed in E. Coli.
- Clone
- 1F4A9
- Isotype
- IgG1
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200-1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
- Autre désignation
- CDKN1C (CDKN1C Produits)
- Synonymes
- anticorps BWCR, anticorps BWS, anticorps KIP2, anticorps WBS, anticorps p57, anticorps p57Kip2, anticorps cb961, anticorps p27Xic1-a, anticorps zgc:86618, anticorps AL024410, anticorps CDKI, anticorps Kip2, anticorps p57(kip2), anticorps p57KIP2, anticorps cyclin dependent kinase inhibitor 1C, anticorps cyclin-dependent kinase inhibitor 1Ca, anticorps cyclin-dependent kinase inhibitor 1C (P57), anticorps cyclin-dependent kinase inhibitor 1C, anticorps CDKN1C, anticorps cdkn1ca, anticorps Cdkn1c
- Sujet
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Description:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Aliases: BWS, WBS, p57, BWCR, KIP2, p57Kip2
- Poids moléculaire
- 32.2kDa
- ID gène
- 1028
- UniProt
- P49918
- Pathways
- Cycle Cellulaire, Dopaminergic Neurogenesis
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