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CDKN1C anticorps

CDKN1C Reactivité: Humain WB, ELISA, FACS, IHC, ICC Hôte: Souris Monoclonal 1F4A9 unconjugated
N° du produit ABIN7193626
  • Antigène Voir toutes CDKN1C Anticorps
    CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
    Reactivité
    • 105
    • 60
    • 28
    • 2
    Humain
    Hôte
    • 73
    • 33
    Souris
    Clonalité
    • 71
    • 35
    Monoclonal
    Conjugué
    • 50
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CDKN1C est non-conjugé
    Application
    • 42
    • 37
    • 35
    • 32
    • 22
    • 14
    • 14
    • 12
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Fonction
    CDKN1C Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human CDKN1C expressed in E. Coli.
    Clone
    1F4A9
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200-1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
    Autre désignation
    CDKN1C (CDKN1C Produits)
    Synonymes
    anticorps BWCR, anticorps BWS, anticorps KIP2, anticorps WBS, anticorps p57, anticorps p57Kip2, anticorps cb961, anticorps p27Xic1-a, anticorps zgc:86618, anticorps AL024410, anticorps CDKI, anticorps Kip2, anticorps p57(kip2), anticorps p57KIP2, anticorps cyclin dependent kinase inhibitor 1C, anticorps cyclin-dependent kinase inhibitor 1Ca, anticorps cyclin-dependent kinase inhibitor 1C (P57), anticorps cyclin-dependent kinase inhibitor 1C, anticorps CDKN1C, anticorps cdkn1ca, anticorps Cdkn1c
    Sujet

    Description:

    This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

    Aliases: BWS, WBS, p57, BWCR, KIP2, p57Kip2

    Poids moléculaire
    32.2kDa
    ID gène
    1028
    UniProt
    P49918
    Pathways
    Cycle Cellulaire, Dopaminergic Neurogenesis
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