CD3D anticorps (AA 127-171)

N° du produit ABIN7193637

Détail du produit anti-CD3D anticorps

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Épitope: AA 127-171

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3D est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: CD3D Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD3D (AA: 127-171) expressed in E. Coli.

Clone: 6B6B12

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200-1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CD3D

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Autre désignation: CD3D (CD3D Produits)

Synonymes: anticorps CD3-DELTA, anticorps T3D, anticorps CD3, anticorps T3d, anticorps CD3d molecule, anticorps CD3 antigen, delta polypeptide, anticorps CD3D, anticorps Cd3d

Sujet:

Description:

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]

Aliases: T3D, IMD19, CD3-DELTA

Poids moléculaire: 18.9kDa

ID gène: 915

UniProt: P04234

Pathways: TCR Signaling, CXCR4-mediated Signaling Events