KRT6A anticorps (AA 253-352)

N° du produit ABIN7193708

Détail du produit anti-KRT6A anticorps

Antigène: KRT6A (Keratin 6A (KRT6A))

Épitope: AA 253-352

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT6A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: KRT6A Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human KRT6A (AA: 253-352) expressed in E. Coli.

Clone: 7E3D1

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur KRT6A

Antigène: KRT6A (Keratin 6A (KRT6A))

Autre désignation: KRT6A (KRT6A Produits)

Synonymes: anticorps CK6A, anticorps CK6C, anticorps CK6D, anticorps K6A, anticorps K6C, anticorps K6D, anticorps KRT6C, anticorps KRT6D, anticorps 2310016L08Rik, anticorps Krt2-6a, anticorps Krt2-6c, anticorps MK6a, anticorps mK6[a], anticorps CK-6A, anticorps Krt6a, anticorps KRT6A, anticorps keratin 6A, anticorps similar to keratin complex 2, basic, gene 6a, anticorps keratin, type II cytoskeletal 6A, anticorps KRT6A, anticorps Krt6a, anticorps LOC683313, anticorps LOC101112304

Sujet:

Description:

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Aliases: KRT6A, K6A, K6C, K6D, PC3, CK6C, CK6D, CK-6C, CK-6E, KRT6C, KRT6D

Poids moléculaire: 60kDa

ID gène: 3853

UniProt: P02538