CXCR6 anticorps

N° du produit ABIN7193912

Détail du produit anti-CXCR6 anticorps

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCR6 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Fonction: CD186 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD186 expressed in E. Coli.

Clone: 2A4D10

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CXCR6

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Autre désignation: CD186 (CXCR6 Produits)

Synonymes: anticorps BONZO, anticorps CD186, anticorps STRL33, anticorps TYMSTR, anticorps BB217514, anticorps C-X-C motif chemokine receptor 6, anticorps chemokine (C-X-C motif) receptor 6 L homeolog, anticorps chemokine (C-X-C motif) receptor 6, anticorps CXCR6, anticorps cxcr6.L, anticorps Cxcr6

Sujet:

Description:

The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4.

Aliases: CXCR6, BONZO, CDw186, STRL33, TYMSTR

Poids moléculaire: 39.3kDa

ID gène: 10663

UniProt: O00574