Integrin beta 7 anticorps (AA 20-174)

N° du produit ABIN7193968

Détail du produit anti-Integrin beta 7 anticorps

Antigène: Integrin beta 7 (ITGB7)

Épitope: AA 20-174

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 7 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Fonction: ITGB7 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ITGB7 (AA: 20-174) expressed in E. Coli.

Clone: 4C5D2

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/50 - 1/200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: ITGB7 (ITGB7 Produits)

Synonymes: anticorps Ly69, anticorps integrin beta 7, anticorps integrin subunit beta 7, anticorps integrin, beta 7, anticorps Itgb7, anticorps ITGB7

Sujet:

This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Poids moléculaire: 86.9kDa

ID gène: 3695

UniProt: P26010

Pathways: Integrin Complex