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Recombinant ErbB2/Her2 (Pertuzumab Biosimilar) anticorps

Reactivité: Humain FACS, in vivo Hôte: Souris Monoclonal unconjugated Recombinant Antibody
N° du produit ABIN7200658
  • Antigène Tous les produits ErbB2/Her2 (Pertuzumab Biosimilar)
    ErbB2/Her2 (Pertuzumab Biosimilar)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    Humain
    Hôte
    • 1
    Souris
    Clonalité
    • 1
    Monoclonal
    Conjugué
    • 1
    Cet anticorp ErbB2/Her2 (Pertuzumab Biosimilar) est non-conjugé
    Application
    Flow Cytometry (FACS), In vivo Studies (in vivo)
    Fonction
    Pertuzumab Biosimilar, Human HER2 Monoclonal Antibody
    Specificité
    The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.
    Attributs du produit
    Recombinant humanized IgG1 Monoclonal Antibody.
    Purification
    Protein A affinity column
    Pureté
    > 95% by SDS-PAGE under reducing conditions and HPLC.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    < 1 EU per 1 mg of the protein by the LAL method.
    Immunogène
    The monoclonal antibody pertuzumab biosimilar was produced in the pertuzumab biosimilar CHO stable cell line.
    Isotype
    IgG1 kappa
  • Indications d'application
    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, pH 7.4, no stabilizers or preservatives.
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
    Date de péremption
    12 months
  • Antigène
    ErbB2/Her2 (Pertuzumab Biosimilar)
    Abstract
    ErbB2/Her2 (Pertuzumab Biosimilar) Produits
    Classe de substances
    Biosimilar
    Sujet
    Pertuzumab, a humanized monoclonal antibody, inhibits HER dimerization and is used for the treatment of HER2-positive metastatic breast cancer, in combination with trastuzumab and docetaxel. By binding to HER2, Pertuzumab inhibits the dimerization of HER2 with other HER receptors, resulting in slowed tumor growth.
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