NCKAP1 anticorps (AA 1001-1132) (Cy5)
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- Antigène Voir toutes NCKAP1 Anticorps
- NCKAP1 (NCK Associated Protein 1 (NCKAP1))
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Épitope
- AA 1001-1132
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NCKAP1 est conjugé à/à la Cy5
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Application
- Western Blotting (WB)
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human NCKAP1L
- Isotype
- IgG
- Top Product
- Discover our top product NCKAP1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- NCKAP1 (NCK Associated Protein 1 (NCKAP1))
- Autre désignation
- NCKAP1 (NCKAP1 Produits)
- Synonymes
- anticorps HEM2, anticorps NAP1, anticorps NAP125, anticorps p125Nap1, anticorps C79304, anticorps H19, anticorps Hem-2, anticorps Hem2, anticorps Nap1, anticorps mKIAA0587, anticorps mh19, anticorps NCK associated protein 1, anticorps NCK-associated protein 1, anticorps NCK-associated protein 1 L homeolog, anticorps NCKAP1, anticorps Nckap1, anticorps nckap1.L
- Sujet
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Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.
Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.
- ID gène
- 10787
- UniProt
- P55160
- Pathways
- Signalisation RTK, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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