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RORB anticorps (AA 385-470) (Biotin)

RORB Reactivité: Souris, Rat WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN715873
  • Antigène Voir toutes RORB Anticorps
    RORB (RAR-Related Orphan Receptor B (RORB))
    Épitope
    • 14
    • 9
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 385-470
    Reactivité
    • 47
    • 26
    • 25
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Souris, Rat
    Hôte
    • 53
    • 8
    Lapin
    Clonalité
    • 53
    • 8
    Polyclonal
    Conjugué
    • 28
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RORB est conjugé à/à la Biotin
    Application
    • 47
    • 22
    • 19
    • 13
    • 13
    • 8
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RORB
    Isotype
    IgG
    Top Product
    Discover our top product RORB Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    RORB (RAR-Related Orphan Receptor B (RORB))
    Autre désignation
    ROR beta (RORB Produits)
    Synonymes
    anticorps RORB, anticorps Nr1f2, anticorps LOC100226267, anticorps NR1F2, anticorps ROR-BETA, anticorps RZR-BETA, anticorps RZRB, anticorps bA133M9.1, anticorps nr1f2, anticorps rzrb, anticorps sb:eu943, anticorps RZR-beta, anticorps Rorbeta, anticorps RAR related orphan receptor B, anticorps RAR-related orphan receptor B, anticorps RAR-related orphan receptor beta, anticorps RORB, anticorps Rorb, anticorps rorb
    Sujet

    Synonyms: NR1F2, Nuclear receptor ROR-beta, Nuclear receptor RZR beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, RAR related orphan receptor B, RAR related orphan receptor beta, Retinoic acid binding receptor beta, Retinoid-related orphan receptor-beta, ROR BETA, Rorb, RORB_HUMAN, RZR BETA, RZRB.

    Background: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)

    ID gène
    6096
    UniProt
    Q92753
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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