beta Catenin anticorps

N° du produit ABIN7202102

Détail du produit anti-beta Catenin anticorps

Antigène: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta Catenin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Catenin-β Monoclonal Antibody

Specificité: The antibody detects endogenous Catenin-β protein.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen

Immunogène: Recombinant Protein

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IF (1:100-1:200), IHC-P (1:200-1:500).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur beta Catenin

Antigène: beta Catenin (CATNB) (Catenin, beta (CATNB))

Autre désignation: Catenin-beta (CATNB Produits)

Synonymes: anticorps Bfc, anticorps Catnb, anticorps Mesc, anticorps CTNNB, anticorps MRD19, anticorps armadillo, anticorps ctnnb, anticorps id:ibd2058, anticorps wu:fb73e10, anticorps wu:fi81c06, anticorps wu:fk25h01, anticorps beta-catenin, anticorps ctnnb1, anticorps CHBCAT, anticorps catenin (cadherin associated protein), beta 1, anticorps catenin beta 1, anticorps catenin (cadherin-associated protein), beta 1, anticorps catenin beta 1 L homeolog, anticorps Ctnnb1, anticorps CTNNB1, anticorps ctnnb1, anticorps ctnnb1.L

Sujet: Mouse Anti-Catenin-β Monoclonal Antibody,The protein encoded by CTNNB1 (catenin beta 1) is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.,Catenin beta-1

ID gène: 1499

UniProt: P35222

Pathways: Peptide Hormone Metabolism