MRGPRX2 anticorps (AA 250-330)

N° du produit ABIN7229756

Détail du produit anti-MRGPRX2 anticorps

Antigène: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Épitope: AA 250-330

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRGPRX2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Fonction: MRGX2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MRGX2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human MRGX2 protein at AA range: 250-330

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MRGPRX2

Antigène: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Autre désignation: MRGX2 (MRGPRX2 Produits)

Synonymes: anticorps MRGX2, anticorps G370024M05Rik, anticorps MrgB10, anticorps Mrgprb10, anticorps MrgB1, anticorps Mrgprb1, anticorps MAS related GPR family member X2, anticorps MAS-related GPR, member X2, anticorps MRGPRX2, anticorps Mrgprx2

Sujet: Rabbit Anti-MRGX2 Polyclonal Antibody,Mas-related G-protein coupled receptor member X2,Mast cell-specific receptor for basic secretagogues, i.e. Cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed: 25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.,MRGX2

Poids moléculaire: observerd band 36kDa

ID gène: 117194

UniProt: Q96LB1