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OPN4 anticorps (AA 400-480)

OPN4 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7215736
  • Antigène Voir toutes OPN4 Anticorps
    OPN4 (Opsin 4 (OPN4))
    Épitope
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 400-480
    Reactivité
    • 7
    • 1
    • 1
    Humain
    Hôte
    • 7
    Lapin
    Clonalité
    • 7
    Polyclonal
    Conjugué
    • 7
    Cet anticorp OPN4 est non-conjugé
    Application
    • 7
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Fonction
    Melanopsin Polyclonal Antibody
    Specificité
    Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Immunogène
    Synthesized peptide derived from the C-terminal region of human Melanopsin at AA range: 400-480
    Isotype
    IgG
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
    Commentaires

    Primary Antibody

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Antigène
    OPN4 (Opsin 4 (OPN4))
    Autre désignation
    Melanopsin (OPN4 Produits)
    Synonymes
    anticorps MOP, anticorps 1110007J02Rik, anticorps Gm533, anticorps OPN4-2, anticorps cOpn4L, anticorps melanopsin, anticorps opn4-A, anticorps Xmop, anticorps opn4, anticorps opn4d, anticorps opsin 4, anticorps opsin 4 (melanopsin), anticorps melanopsin, anticorps melanopsin-B-like L homeolog, anticorps opsin 4a (melanopsin), anticorps OPN4, anticorps Opn4, anticorps LOC100303707, anticorps LOC100485437.L, anticorps opn4a
    Sujet
    Rabbit Anti-Melanopsin Polyclonal Antibody,OPN4, MOP, Melanopsin, Opsin-4,Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. OPN4 encodes a photoreceptive opsin protein melanopsin that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. Melanopsin functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.,Melanopsin
    Poids moléculaire
    observerd band 55kDa
    ID gène
    94233
    UniProt
    Q9UHM6
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