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EMP2 anticorps (AA 65-167)

EMP2 Reactivité: Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN716576
  • Antigène Tous les produits EMP2
    EMP2 (Epithelial Membrane Protein 2 (EMP2))
    Épitope
    • 14
    • 9
    • 8
    • 8
    • 4
    • 2
    AA 65-167
    Reactivité
    • 18
    • 15
    • 14
    • 1
    Rat
    Hôte
    • 44
    Lapin
    Clonalité
    • 44
    Polyclonal
    Conjugué
    • 11
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EMP2 est non-conjugé
    Application
    • 33
    • 18
    • 18
    • 12
    • 12
    • 7
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EMP2
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Torella, Iaconetti, Tarallo, Marino, Giurato, Veneziano, Aquila, Scalise, Mancuso, Cianflone, Valeriano, Marotta, Tammè, Vicinanza, Sasso, Cozzolino, Torella, Weisz, Indolfi: "miRNA Regulation of the Hyperproliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes." dans: Diabetes, Vol. 67, Issue 12, pp. 2554-2568, (2019) (PubMed).

  • Antigène
    EMP2 (Epithelial Membrane Protein 2 (EMP2))
    Autre désignation
    Emp2 (EMP2 Produits)
    Synonymes
    anticorps MGC52916, anticorps MGC130799, anticorps MGC69514, anticorps emp2, anticorps XMP, anticorps epithelial membrane protein 2 L homeolog, anticorps epithelial membrane protein 2, anticorps emp2.L, anticorps emp2, anticorps EMP2, anticorps Emp2
    Sujet

    Synonyms: EMP-2, EMP2, EMP2_HUMAN, Epithelial membrane protein 2, Protein XMP.

    Background: EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.

    ID gène
    2013
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