TEAD2 anticorps (AA 40-120)

N° du produit ABIN7225436

Détail du produit anti-TEAD2 anticorps

Antigène: TEAD2 (TEA Domain Family Member 2 (TEAD2))

Épitope: AA 40-120

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEAD2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: TEF-4 Polyclonal Antibody

Specificité: TEF-4 Polyclonal Antibody detects endogenous levels of TEF-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human TEF-4 at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur TEAD2

Antigène: TEAD2 (TEA Domain Family Member 2 (TEAD2))

Autre désignation: TEF-4 (TEAD2 Produits)

Synonymes: anticorps TEAD2, anticorps ETF, anticorps TEAD-2, anticorps TEF-4, anticorps TEF4, anticorps Etdf, anticorps TEA domain transcription factor 2, anticorps TEA domain family member 2, anticorps TEAD2, anticorps Tead2

Sujet: Rabbit Anti-TEF-4 Polyclonal Antibody,TEAD2, TEF4, Transcriptional enhancer factor TEF-4, TEA domain family member 2, TEAD-2,The Hippo pathway is an important evolutionarily conserved signaling pathway that controls organ size and tumor suppression by inhibiting cell proliferation and promoting apoptosis. An integral function of the Hippo pathway is to repress the activity of Yes-associated protein (YAP), a proposed oncogene whose activity is regulated by phosphorylation and subcellular localization. When the Hippo pathway is turned off, YAP is phosphorylated and translocates to the nucleus where it associates with various transcription factors including members of the transcriptional enhancer factor (TEF) family, also known as the TEA domain (TEAD) family (TEAD1-4). Although widely expressed in tissues, the TEAD family proteins have specific tissue and developmental distributions. YAP/TEAD complexes regulate the expression of genes involved in cell proliferation and apoptosis.,Transcriptional enhancer factor TEF-4

ID gène: 8463

UniProt: Q15562

Pathways: Regulation of Lipid Metabolism by PPARalpha, Tube Formation