TNFRSF11A anticorps (AA 60-120)
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- Antigène Voir toutes TNFRSF11A Anticorps
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
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Épitope
- AA 60-120
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TNFRSF11A est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- RANK Polyclonal Antibody
- Specificité
- The antibody detects endogenous levels of RANK
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
- Immunogène
- Synthesized peptide derived from part region of human RANK protein at AA range: 60-120
- Isotype
- IgG
- Top Product
- Discover our top product TNFRSF11A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:500-1:200), ELISA (1:10000-1:20000).
- Commentaires
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Primary Antibody
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Antigène
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
- Autre désignation
- RANK (TNFRSF11A Produits)
- Synonymes
- anticorps RANK, anticorps RGD1563614, anticorps TNFRSF11A, anticorps Ly109, anticorps ODFR, anticorps OFE, anticorps Rank, anticorps TRANCE-R, anticorps mRANK, anticorps CD265, anticorps FEO, anticorps LOH18CR1, anticorps OPTB7, anticorps OSTS, anticorps PDB2, anticorps TRANCER, anticorps TNF receptor superfamily member 11A, anticorps TNF receptor superfamily member 11a, anticorps tumor necrosis factor receptor superfamily, member 11a, NFKB activator, anticorps Tnfrsf11a, anticorps TNFRSF11A
- Sujet
- Rabbit Anti-RANK Polyclonal Antibody,Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, ODFR, Receptor activator of NF-KB, CD antigen CD265,TNFRSF11A (TNF Receptor Superfamily Member 11a) is a Protein Coding gene. Diseases associated with TNFRSF11A include Osteopetrosis, Autosomal Recessive 7 and Osteolysis, Familial Expansile. Among its related pathways are Akt Signaling and CDK-mediated phosphorylation and removal of Cdc6. The protein encoded by TNFRSF11A is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.,RANK
- Poids moléculaire
- observerd band 66kDa
- ID gène
- 8792
- UniProt
- Q9Y6Q6
- Pathways
- Signalisation NF-kappaB
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