GLI1 anticorps (AA 460-490)

N° du produit ABIN7228664

Détail du produit anti-GLI1 anticorps

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Épitope: AA 460-490

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: GLI-1 Polyclonal Antibody

Specificité: This antibody detects endogenous levels of GLI-1

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human GLI-1 protein at AA range: 460-490

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur GLI1

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Autre désignation: GLI-1 (GLI1 Produits)

Synonymes: anticorps GLI, anticorps Gli, anticorps Gli-1, anticorps gli1.1, anticorps AV235269, anticorps Zfp-5, anticorps Zfp5, anticorps GLI family zinc finger 1, anticorps GLI family zinc finger 1 S homeolog, anticorps GLI-Kruppel family member GLI1, anticorps GLI1, anticorps Gli1, anticorps gli1.S, anticorps gli1

Sujet: Rabbit Anti-GLI-1 Polyclonal Antibody,Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI,GLI1 encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.,GLI-1

Poids moléculaire: observerd band 120kDa

ID gène: 2735

UniProt: P08151

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis