This antibody recognizes human, mouse, and rat PCDHG-A, B, and C proteins
Réactivité croisée
Humain, Souris, Rat
Immunogène
Fusion protein corresponding to aa 808-931 (C-terminal cytoplasmic constant domain) of mouse PCDHGA1. This sequence is present in all 22 PCDHG proteins.
Immunoblotting: use at 1-2 μg/mL. A band of ~100 kDa is detected. Immunofluorescence: use at 10 μg/mL. These are recommended concentrations. Endusers should determine optimal concentrations for their application.
Restrictions
For Research Use only
Format
Liquid
Reconstitution
Dilute in PBS or medium that is identical to that used in the assay system.
Concentration
1.0 mg/mL
Buffer
PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
This product is stable for at least one (1) year at -20°C.
Protocadherin γ A1,The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. The gamma gene cluster includes 22 genes divided into 3 subfamilies: subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region (which includes 6 cadherin ectodomains and a trans-membrane region). The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins are believed to play a critical role in the establishment and function of specific cell-cell connections in the brain.