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ABI2 anticorps (AA 100-200)

ABI2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7265360
  • Antigène Voir toutes ABI2 Anticorps
    ABI2 (Abl-Interactor 2 (ABI2))
    Épitope
    • 15
    • 12
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 100-200
    Reactivité
    • 40
    • 16
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 39
    • 2
    Lapin
    Clonalité
    • 40
    • 1
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ABI2 est non-conjugé
    Application
    • 28
    • 21
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    ABI2 Rabbit pAb
    Séquence
    HKEKVARREI GILTTNKNTS RTHKIIAPAN LERPVRYIRK PIDYTILDDI GHGVKWLLRF KVSTQNMKMG GLPRTTPPTQ KPPSPPMSGK GTLGRHSPYR T
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ABI2 (NP_001269854.1).
    Isotype
    IgG
    Top Product
    Discover our top product ABI2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ABI2 (Abl-Interactor 2 (ABI2))
    Autre désignation
    ABI2 (ABI2 Produits)
    Synonymes
    anticorps ABI-2, anticorps ABI2B, anticorps AIP-1, anticorps AblBP3, anticorps SSH3BP2, anticorps argBPIA, anticorps argBPIB, anticorps 8430425M24Rik, anticorps AI839867, anticorps C130078H13, anticorps abl interactor 2, anticorps abl-interactor 2, anticorps ABI2, anticorps abi2, anticorps Abi2
    Sujet
    Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation. Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge. Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (By similarity. In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (By similarity. Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (By similarity. Also required for nascent adherens junction assembly in epithelial cells.,ABI2,ABI-2,ABI2B,AIP-1,AblBP3,SSH3BP2,argBP1,argBPIA,argBPIB,Cancer,Tumor suppressors,ABI2
    Poids moléculaire
    44kDa/52kDa/54kDa/55kDa
    ID gène
    10152
    UniProt
    Q9NYB9
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