anticorps APRIL, anticorps PHAPI2, anticorps SSP29, anticorps 2410015B15Rik, anticorps PAL31, anticorps PHAPI2a, anticorps Ssp29, anticorps cb908, anticorps fa99a11, anticorps wu:fa28c10, anticorps wu:fa99a11, anticorps wu:fb40e12, anticorps zgc:77745, anticorps hLAMP-1, anticorps MGC80871, anticorps ANP32B, anticorps MGC69373, anticorps SLAN, anticorps acidic nuclear phosphoprotein 32 family member B, anticorps acidic (leucine-rich) nuclear phosphoprotein 32 family, member B, anticorps acidic nuclear phosphoprotein 32 family member B L homeolog, anticorps acidic leucine-rich nuclear phosphoprotein 32 family member B, anticorps ANP32B, anticorps Anp32b, anticorps anp32b, anticorps anp32b.L, anticorps LOC494442
Sujet
Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription. Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis. Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes. Plays also an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1. Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (By similarity.,APRIL, PHAPI2, SSP29,Apoptosis,Apoptosis_Caspases,Cell Biology & Developmental Biology,Cell Cycle,ANP32B