ADRA2C anticorps (AA 240-380)

N° du produit ABIN7265501

Détail du produit anti-ADRA2C anticorps

Antigène: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Épitope: AA 240-380

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2C est non-conjugé

Application: Western Blotting (WB)

Fonction: ADRA2C Rabbit pAb

Séquence: RTRTLSEKRA PVGPDGASPT TENGLGAAAG AGENGHCAPP PADVEPDESS AAAERRRRRG ALRRGGRRRA GAEGGAGGAD GQGAGPGAAE SGALTASRSP GPGGRLSRAS SRSVEFFLSR RRRARSSVCR RKVAQAREKR F

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ADRA2C (NP_000674.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ADRA2C

Antigène: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Autre désignation: ADRA2C (ADRA2C Produits)

Synonymes: anticorps ADRA2L2, anticorps ADRA2RL2, anticorps ADRARL2, anticorps ALPHA2CAR, anticorps Adra-2c, anticorps [a]2C, anticorps alpha2-C4, anticorps alpha2C, anticorps zgc:194523, anticorps zgc:194541, anticorps adra2c, anticorps ADRA2B, anticorps ADRA2C, anticorps adrenoceptor alpha 2C, anticorps adrenergic receptor, alpha 2c, anticorps ADRA2C, anticorps Adra2c, anticorps adra2c

Sujet: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008],ADRA2L2,ADRA2RL2,ADRARL2,ALPHA2CAR,ADRA2C,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,ADRA2C

ID gène: 152

UniProt: P18825

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process