anticorps AKR1C-pseudo, anticorps BABP, anticorps DD, anticorps DD2, anticorps DDH2, anticorps HAKRD, anticorps HBAB, anticorps MCDR2, anticorps SRXY8, anticorps Akr1c21, anticorps aldo-keto reductase family 1 member C2, anticorps aldo-keto reductase family 1, member C2, anticorps AKR1C2, anticorps Akr1c2
Sujet
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.,AKR1C2,AKR1C-pseudo,BABP,DD,DD-2,DD/BABP,DD2,DDH2,HAKRD,HBAB,MCDR2,SRXY8,TDD,AKR1C2