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alpha 2 Macroglobulin anticorps

A2M Reactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated
N° du produit ABIN7265558
  • Antigène Voir toutes alpha 2 Macroglobulin (A2M) Anticorps
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    Reactivité
    • 99
    • 22
    • 19
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 94
    • 19
    • 17
    • 4
    • 1
    • 1
    Lapin
    Clonalité
    • 110
    • 24
    Monoclonal
    Conjugué
    • 77
    • 19
    • 12
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp alpha 2 Macroglobulin est non-conjugé
    Application
    • 80
    • 49
    • 37
    • 19
    • 14
    • 10
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Fonction
    Alpha-2-Macroglobulin (A2M) Rabbit mAb
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthesized peptide derived from human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M))
    Isotype
    IgG
    Top Product
    Discover our top product A2M Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    Autre désignation
    A2M (A2M Produits)
    Sujet
    The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016],A2MD, CPAMD5, FWP007, S863-7,Blood,Blood_Serum Proteins,Cardiovascular,Cell Biology & Developmental Biology,Ubiquitin,A2M
    Poids moléculaire
    163kDa
    ID gène
    2
    UniProt
    P01023
    Pathways
    Lipid Metabolism
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