anticorps MGC98869, anticorps BRMS1, anticorps BRMS1L, anticorps AV003220, anticorps AW554636, anticorps si:zc188c22.3, anticorps si:zc194c5.2, anticorps wu:fb57b08, anticorps zgc:56414, anticorps breast cancer metastasis suppressor 1, anticorps breast cancer metastasis-suppressor 1, anticorps breast cancer metastasis suppressor 1 L homeolog, anticorps BRMS1, anticorps Brms1, anticorps brms1.L, anticorps brms1
Sujet
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.,BRMS1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,BRMS1