CRADD anticorps

N° du produit ABIN7266106

Détail du produit anti-CRADD anticorps

Antigène: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CRADD est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: RAIDD/CRADD Rabbit mAb

Réactivité croisée: Humain, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human RAIDD/CRADD

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CRADD

Antigène: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Autre désignation: CRADD (CRADD Produits)

Synonymes: anticorps cradd, anticorps MGC89035, anticorps zgc:101717, anticorps CRADD, anticorps DKFZp468A2219, anticorps LOC100226369, anticorps raidd, anticorps MGC78788, anticorps MRT34, anticorps RAIDD, anticorps CASP2 and RIPK1 domain containing adaptor with death domain, anticorps CASP2 and RIPK1 domain containing adaptor with death, gene 1, anticorps CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog, anticorps CRADD, anticorps cradd.1, anticorps cradd, anticorps cradd.2.S, anticorps Cradd

Sujet: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],MRT34, RAIDD,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cancer,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Invasion and Metastasis,CRADD

Poids moléculaire: 23kDa

ID gène: 8738

UniProt: P78560

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity